Protagonist Therapeutics

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Protagonist Therapeutics: Proprietary peptide technology platform to develop oral targeted therapy-based drugs and injectables for rare diseases. PTG-300 injectable hepcidin mimetic Ph 2 trials ongoing in polycythemia vera and hereditary hemochromatosis; positive updated Ph 2 results in PV presented at ASH 2020. PN-943 oral GI-restricted alpha-4-beta-7 antagonist Ph 2 in ulcerative colitis study sites activated; PTG-200, partnered w/ Janssen, oral GI-restricted IL-23R antagonist Ph 2 Crohn’s disease study ongoing.
Based in...
US - Pacific
Clinical Stage
Phase l or ll
Disease Space
Anti-inflammatory, Autoimmune, Gastrointestinal, Rare Disease
Public, USA
Market Cap
500MM - 1B
Therapeutic Modalities
Platform Technology
521 Cottonwood Drive
Suite 100
Milpitas, CA 95035
United States

Company Participants at Protagonist Therapeutics Virtual KOL Event following ASH

  • Dinesh V Patel, PhD, President & CEO

Top 10 Holders of Protagonist Therapeutics, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
SSgA Funds Management, Inc. 13.93 6,776,269 77.66 Stakes 6/30/22
Fidelity Management & Research Co. LLC 13.07 6,325,237 72.49 13F 3/31/22
RTW Investments LP 9.90 4,794,499 54.94 13F 3/31/22
Point72 Asset Management LP 9.07 4,312,300 49.42 Stakes 9/20/21
BVF, Inc. 8.64 4,183,219 47.94 13F 3/31/22
State Street Corp. 6.73 3,256,808 37.32 13F 3/31/22
Point72 Asset Management LP (Old) 6.02 2,915,100 33.41 13F 3/31/22
Johnson & Johnson 5.06 2,449,183 28.07 13F 3/31/22
The Vanguard Group, Inc. 4.76 2,311,347 26.49 Funds 6/30/22
Vanguard Group, Inc. (Subfiler) 4.58 2,216,880 25.41 13F 3/31/22
Ownership data is sourced through FactSet.

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