Iovance Biotherapeutics

Iovance Biotherapeutics: Developing novel cancer immunotherapies based on tumor infiltrating lymphocytes (TIL) for the treatment of solid tumors. TIL therapy is a highly personalized approach in which patients receive a one-time treatment with their own expanded and rejuvenated T-cells to treat cancer. BLA expected in August 2022 following completion of pivotal study of Lifileucel/LN-144 for treatment of Melanoma. Other indications include Cervical, NSCL and HNSC Cancers.
Sector/Industry:
Healthcare/Biotechnology
Characteristics:
Based in...
US - Pacific
Clinical Stage
Registration Stage
Disease Space
Immuno-Oncology, Immunotherapy
Finance
Pre-Revenues
Industry
Biotechnology
Listing
Public, USA
Market Cap
1B +
Therapeutic Modalities
Cell Therapy
Website:
Address:
999 Skyway Road
Suite 150
San Carlos, CA 94070
United States

Company Participants at Solebury Trout Virtual Management Access Event 2021

Maria Fardis, Ph.D.
Iovance Biotherapeutics, President/CEO
Dr. Maria Fardis serves as President, Chief Executive Officer and President at Iovance Biotherapeutics. She serves as Board Member at Kartos Therapeutics. She has extensive experience in drug development and novel cancer treatments. Prior to joining Lion Biotechnologies, Dr. Fardis was chief operating officer at Acerta Pharma working on the development of acalabrutinib until the company's acquisition by AstraZeneca. Before joining Acerta, Dr. Fardis held the position of chief of oncology operations and alliances at Pharmacyclics where she oversaw development of ibrutinib (IMBRUVICA®), abexinostat (HDAC inhibitor), and FVIIa inhibitor programs. She was a key contributor in the creation of a broad clinical program for ibrutinib, as well as NDA and MAA submissions. Previously, Dr. Fardis held a number of key scientific and management roles at Gilead Sciences. At Gilead, she was involved with multiple therapeutic areas including antivirals, oncology, and cardiovascular therapeutics and worked on the development and life cycle management of ambrisentan (Letairis®). She received her PhD in organic chemistry from UC Berkeley and holds an MBA from Golden Gate University.
Sara Pellegrino
Iovance Biotherapeutics, VP:IR & Public Relations
Dr. Fardis joined Iovance as President and Chief Executive Officer, and was appointed to the Company’s Board of Directors, in 2016. Prior to Iovance, Dr. Fardis served as the Chief Operating Officer of Acerta Pharma B.V., a clinical-stage biopharmaceutical company, where she worked on the development of Calquence® until the company’s acquisition by AstraZeneca. Previously, Dr. Fardis worked at Pharmacyclics, Inc., where she was a key contributor in the creation of a broad clinical program leading to global approvals for Imbruvica® in multiple hematologic malignancies, and where she served as Chief of Oncology Operations and Alliances. Prior to joining Pharmacyclics, Dr. Fardis held increasingly senior positions in Medicinal Chemistry and the project and portfolio management department at Gilead Sciences, Inc., where she was involved with multiple therapeutic areas including antivirals, oncology, and cardiovascular therapeutics and worked on the development and life cycle management of Letairis®. Dr. Fardis received her Ph.D. in Organic Chemistry from the University of California, Berkeley and her B.S., summa cum laude, in Chemistry from the University of Illinois, Urbana-Champaign. Dr. Fardis holds an M.B.A., with highest honors, from Golden Gate University.

Top 10 Holders of Iovance Biotherapeutics Inc

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Perceptive Advisors LLC 7.76 12,201,261 148.61 13F 3/31/22
The Vanguard Group, Inc. 7.77 12,197,787 148.57 Stakes 12/31/21
Vanguard Group, Inc. (Subfiler) 7.75 12,178,378 148.33 13F 3/31/22
Wellington Management Co. LLP 7.18 11,288,726 137.50 13F 3/31/22
Avoro Capital Advisor LLC 5.81 9,125,000 111.14 13F 3/31/22
State Street Corp. 4.36 6,845,726 83.38 13F 3/31/22
OrbiMed Advisors LLC 4.22 6,633,006 80.79 13F 3/31/22
Farallon Capital Management LLC 3.93 6,175,357 75.22 13F 3/31/22
Avidity Partners Management LP 3.85 6,043,219 73.61 13F 3/31/22
Franklin Advisers, Inc. 3.41 5,359,423 65.28 13F 3/31/22
Ownership data is sourced through FactSet.

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